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It is known that the presence of a carbonyl group at C2 in norbornane compounds aids in the S N 2 displacement of substituents at C7. In this study, we report a significant enhancement in reactivity at C7 by a second carbonyl group at C3. These diketones undergo rapid inversion at 80 o C, while the monoketone does not exhibit any reactivity at this temperature. The increase in reactivity...
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