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Abstract. Rat parotid acinar cells were perfused in small quartz columns to examine the role of cAMP and Ca2+ in the priming and fusion/exocytosis of amylase secretion. Carbachol (CCh) evoked a biphasic response of amylase secretion with an initial rapidly occurring large peak and a subsequent sustained plateau. Isoproterenol produced slowly increasing amylase secretion that reached the plateau greater...
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