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In this article, we address the integration of design and nonlinear model‐based control under uncertainty and structural decisions for naturally ordered structures. We propose an algorithmic framework to determine the optimal location of process units or streams over an ordered discrete set that operates in closed‐loop with a model‐based controller. The formulation corresponds to a mixed‐integer bilevel...
A previously developed equation-based flowsheet optimization framework is extended and applied to design sub-ambient separation systems for oxy-fired coal power systems with carbon capture. Unlike most commercial flowsheet design and optimization tools, the proposed methods use exact derivatives and large-scale nonlinear programming algorithms to solve large flowsheet design problems with many degrees...
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