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Purpose ABT-414 is an antibody-drug conjugate (ADC) being developed for the treatment of tumors harboring amplification of the epidermal growth factor receptor (EGFR). This study evaluated the potential of ABT-414 to prolong the QT interval as part of the initial phase 1 study (NCT01741727). Methods Data from patients who received ABT-414 monotherapy at a dose of 1–4 mg/kg once every 3 weeks or...
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