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Aquated cisplatin was added to half-generation PAMAM dendrimers and the resultant complexes were purified by centrifuge. The drug–dendrimer complexes were then characterised by 1-D and diffusion 1 H NMR and ICP-AES. The amount of drug bound was found to increase in proportion with dendrimer size: G3.5, 22 cis-{Pt(NH 3 ) 2 } molecules per dendrimer; G4.5, 37; G5.5, 54; and G6...
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