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Hydrogen sulfide (H2S) is an important endogenous signaling molecule with a variety of biological functions. To detect H2S in living biological systems, herein we developed a new fluorescent probe for highly sensitive and selective sensing of H2S in cells. The probe is based on coumarin–triazole as the fluorophore and thiolysis of the NBD (7-nitro-1,2,3-benzoxadiazole) amine as the receptor. Bioimaging...
The two signaling molecules H2S and H2O2 play key roles in maintaining intracellular redox homeostasis. The biological relationship between H2O2 and H2S remains largely unknown in redox biology. In this study, we rationally designed and synthesized single‐ and dual‐response fluorescent probes for detecting both H2O2 and H2S in living cells. The dual‐response probe was shown to be capable of mono‐...
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