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Scope
Previous studies indicate that dihydromyricetin (DHM) effectively improved glucose homeostasis and alleviated insulin resistance in population‐intervened trials, yet the underlying mechanism remains obscure.
Methods and results
Wild‐type male mice and recombinase activating gene 1(Rag1)–/– mice (lacking adaptive immunity lymphocytes) are fed with control, high‐fat diet (HFD), or HFD+DHM diets...
Increasing evidence demonstrates that pyroptosis, pro‐inflammatory programmed cell death, is linked to atherosclerosis; however, the underlying mechanisms remain to be elucidated. Dihydromyricetin (DHM), a natural flavonoid, was reported to exert anti‐oxidative and anti‐inflammatory bioactivities. However, the effect of DHM on atherosclerosis‐related pyroptosis has not been studied. In the present...
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