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Objective. The objectives of this study were to identify and determine the validity of early decision criteria following once‐daily gastroretentive gabapentin (G‐GR) treatment in patients with postherpetic neuralgia (PHN).
Design. In two placebo‐controlled studies, 279 patients were randomized to 1,800 mg G‐GR and 270 to placebo with the evening meal; patients underwent a 2‐week dose titration,...
The best-known complication of shingles (herpes zoster) is postherpetic neuralgia (PHN). PHN is commonly studied to investigate causes of and treatments for neuropathic pain. However, many patients with shingles experience neuropathic itch accompanying, or instead of, pain. Some report severe disabling postherpetic itch (PHI), and though it is rare, some patients injure themselves by scratching itchy...
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