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The purpose of this study was to evaluate the effect of tumor size on the uptake of18F-fluorodeoxyglucose (FDG) and fluoroerythronitroimidazole (FETNIM) in a murine sarcoma model. ICR mice were xenografted with sarcoma 180 cell line and tumors were allowed to grow to a weight of 0.26–5.82 grams.18F-FDG and18F-FETNIM were injected intravenously in separate groups of mice, and after 1 hr, the tumors...
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