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The significant impact of drug-loaded nanocarriers on cancer chemotherapy lies in the ability to specifically target to tumors with alleviated systemic toxicities. In the current study, a versatile and scalable method has been developed to construct fiber rods from electrospun fibers by ultrasonication using encapsulated NaCl nanoparticles as void-precursors. The shape effects of doxorubicin (DOX)-loaded...
Micelles self-assembled from drug-conjugated polymers indicate advantages in alleviating the premature release before reaching the intended site. Hyaluronic acid (HA) is known to specifically bind with a transmembrane glycoprotein CD44, overexpressed in many types of cancerous cells, and can also be served as micelle carriers. However, an excess amount of drug conjugation to HA backbone may be detrimental...
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