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The purpose of this work is to study the apparent solid-state kinetics of the Maillard reaction of the colyophilized metoclopramide hydrochloride (MCP) and lactose system and to elucidate some of the effects of molecular mobility on the kinetic behavior of the amorphous mixture. Colyophilized MCP–lactose mixtures (1:9 molar ratio) were stored at temperatures ranging from 100 to 115°C (above the glass...
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