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Hyaluronan (Hyal) was modified by the insertion of sulphate to hydroxyl groups. A series of heparin-like compounds with controllable properties was obtained. The physicochemical and biological behaviours of all these sulphated hyaluronan acids (HyalS x ) and their complexes with heavy metal ions (Cu 2+ and Zn 2+ ) were investigated. HyalS x derivatives showed a good...
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