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In order to expand the scope of protection of the amino group of chitosan for synthesizing a key intermediate that would allow regioselective modification reactions, dichlorophthaloylation behavior was studied in detail. The reaction proceeded in a similar manner to phthaloylation, and chemoselectively protected N-dichlorophthaloyl-chitosan could be prepared either by partial hydrolysis of N,O-dichlorophthaloylated...
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