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The expression of eukaryotic genes is precisely controlled by interactions between general transcriptional factors and promoter‐specific transcriptional activators. The fourth element of TATA‐box binding protein‐associated factor (TAF4), an essential subunit of the general transcription factor TFIID, serves as a coactivator for various promoter‐specific transcriptional regulators. Interactions between...
The expression of eukaryotic genes is precisely controlled by specific interactions between general transcription initiation factors and gene‐specific transcriptional activators. The general transcription factor TFIID, which plays an essential role in mediating transcriptional activation, is a multisubunit complex comprising the TATA box‐binding protein (TBP) and multiple TBP‐associated factors (TAFs)...
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