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Amyloid beta peptide (Aβ) is a small peptide present in normal cells and aggregated Aβ is the main constituent of the extracellular amyloid plaques found in Alzheimer’s disease (AD) brain. Recent studies suggest that soluble Aβ oligomers are neurotoxic rather than amyloid fibrils found in amyloid plaques. This study using multidimensional NMR spectroscopy and circular dichroism (CD) provides the first...
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