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A series of novel 6-phenylaminopurines have been efficiently synthesized in 3 steps exploring different groups at positions 2, 8 and 9 of the purine ring and at the exocyclic nitrogen atom at position 6. Among the newly described purines, five compounds showed antiproliferative activity with IC 50 values below 10 μM, the tetrahydroquinoline derivative at position 6 of phenylaminopurine being...
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