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Experimental measurements have shown that trimethylamine N-oxide, TMAO, is able to stabilize the globule state of PNIPAM [Phys.Chem.Chem.Phys. 2016; 18:31459], the same effect it has towards the native state of globular proteins. The TMAO stabilizing action is rationalized by means of the same theoretical approach used to address the entropic driving force and the effect of sodium salts, urea and...
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