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Bovine seminal ribonuclease is the only pancreatic-type ribonuclease to possess a dimeric structure: the two identical subunits are covalently linked by two disulfide bridges. Actually, the protein exists in two different dimeric structures owing to the possibility of swapping the N-terminal α-helical segments: the swapped MxM dimer, and the non-swapped M=M dimer. The thermal denaturation of the two...
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