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Background
Nonacog alfa, a standard half‐life recombinant factor IX (FIX), is used as a prophylactic treatment in severe haemophilia B (SHB) patients. Its half‐life determined in clinical studies involving a limited sampling (72 h) was shown to be rather short. In our clinical practice, we suspected that its half‐life could have been underestimated.
Objectives
We aimed to evaluate nonacog alfa...
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