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Ca 2+ - and calmodulin-dependent protein kinase III (CaM PKIII) phosphorylates eukaryotic elongation factor 2 (eEF-2) in HL-60 cells. Dephosphorylation of the factor in these cells is catalyzed by phosphoprotein phosphatase 2A alone. Differentiation of the HL-60 cells by all-trans retinoic acid resulted in a reduced growth rate and a marked decrease in the intracellular concentration...
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