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αVβ3 Integrins are a widely recognized target for in vivo molecular imaging of pathological conditions such as inflammation, cancer and rheumatoid arthritis. We have evaluated the sensitivity of a new, near‐infrared fluorescence (NIRF), RGD cyclic probe (DA364) in noninvasive detection of αVβ3 integrin‐overexpressing tumors. DA364's binding affinity for αVβ3 integrin was first evaluated in vitro....
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