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The halogenase‐based catalysis is one of the most environmentally friendly methods for the synthesis of halogenated products, among which flavin‐dependent halogenases (FDHs) have attracted great interest as one of the most promising biocatalysts due to the remarkable site‐selectivity and wide substrate range. However, the complexity of constructing the NAD+‐NADH‐FAD‐FADH2 bicoenzyme cycle system has...