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To study the effect of interleukin-18 gene transfection on the tumorigenesis of breast cancer cell line Bacp37, human breast cancer cell line Bcap37 were transfected with Lipofectamine and selected by G418. The biological expression of rhlL-18 was tested by RT-PCR and ELISA method; nude mice were injected with Bcap37 cell with or without the hlL-18 gene. The hIL-18 cDNA was successfully integrated...
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