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It has been established that voltage‐gated proton channels (VSOP/Hv1), encoded by Hvcn1, support reactive oxygen species (ROS) production in phagocytic activities of neutrophils (El Chemaly et al. [El Chemaly A., 2010]) and antibody production in B lymphocytes (Capasso et al. [Capasso M., 2010]). VSOP/Hv1 is a potential therapeutic target for brain ischemia, since Hvcn1 deficiency reduces microglial...
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