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A new multiple testing procedure, called the FDRL procedure, was proposed by Zhang et al. (Ann Stat 39:613–642, 2011) for detecting the presence of spatial signals for large-scale 2D and 3D imaging data. In contrast to the conventional multiple testing procedure, the FDRL procedure substitutes each p-value by a locally aggregated median filter of p-values. This paper examines the performance of...
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