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BackgroundClinical studies demonstrate synergistic liver damage by alcohol and hepatitis C virus (HCV); however, the mechanisms by which alcohol promotes HCV infection remain obscure. The liver‐specific microRNA‐122 (miR‐122) regulates HCV replication and expression of host genes, including Cyclin G1. Here, we hypothesized that alcohol regulates miR‐122 expression and thereby modulates HCV RNA replication...
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