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Objective: To evaluate 2 hindlimb skeletal muscles in young and aged rats for presence of immature myosin heavy chain (MHC) isoforms. Design: Randomized controlled trial. Setting: Basic science laboratory. Animals: Fisher 344 Brown Norway F1 hybrid rats, ages 12 and 36 months. Interventions: The soleus and extensor digitorum longus (EDL) muscles of young (12mo old) and aged (36mo old) sedentary rats...
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