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The recent successful breakthrough of sub-3μm shell particles in HPLC has triggered considerable research efforts toward the design of new brands of core-shell particles. We investigated the mass transfer mechanism of a few analytes in narrow-bore columns packed with prototype 1.7μm shell particles, made of 1.0, 1.2, and 1.4μm solid nonporous cores surrounded by porous shells 350, 250, and 150nm thick,...
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