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In this study, a comprehensive 2‐D chromatography was constructed, consisting of normal phase LC (NPLC) with a CN column as the first dimension, and supercritical fluid chromatography (SFC), with a Merck Chromolith Flash C18 column as the second dimension, which were connected by a 10‐port, dual‐position valve controlled automatically by a self‐designed software. Such platform was applied into the...
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