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DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) Langmuir monolayers were employed as model membranes for the studies of interactions with an amphiphilic drug — ibuprofen. The mode of interactions was found to be ibuprofen concentration dependent. The maximal value of compressibility constant, 270 mN/m is obtained for ibuprofen 10 −5 –10 −6 M solutions indicating that already in...
Monomolecular films of amphiphilic derivatives of crown ethers bearing an azo group in the macrocycle were prepared on surfaces of pure water or aqueous solutions of alkali metal cations, and studied using the surface pressure and surface potential measurements. The organization of the azocrown molecules in monolayers at the air–water interface was found to depend on the geometry around the –NN– moiety...
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