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Insulin Delivery
In article number 2210392, Christoph E. Hagemeyer, Francesca Cavalieri, and co‐workers report how biodegradable and charge‐switchable phytoglycogen nanoparticles with glucose‐sensitive phenylboronic acid groups and amine moieties can be engineered to form nanocomplexes with insulin for its rapid and efficient glucose‐responsive delivery. Subcutaneous injection of nanocomplexes in...
Glucose‐responsive insulin‐delivery platforms that are sensitive to dynamic glucose concentration fluctuations and provide both rapid and prolonged insulin release have great potential to control hyperglycemia and avoid hypoglycemia diabetes. Here, biodegradable and charge‐switchable phytoglycogen nanoparticles capable of glucose‐stimulated insulin release are engineered. The nanoparticles are “nanosugars”...
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