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Preclinical evidence implicates the serotonin receptor 5-hydroxytryptamine 1B (5-HT 1B ) in the effects of cocaine. This study explores 5-HT 1B in humans by examining receptor availability in vivo in subjects whose primary addiction is cocaine dependence (CD) using positron emission tomography.Study participants included 14 medically healthy subjects with CD (mean age = 41 ± 6 years)...
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