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Inducible hypercapnia is an alternative for increasing the coronary blood flow necessary to facilitate the quantification of myocardial blood flow during hyperemia. The current study aimed to quantify the pharmacokinetic effect of a CO2 gas challenge on myocardial perfusion in rats using high‐resolution, first‐pass perfusion CMR and compared it with pharmacologically induced hyperemia using regadenoson...
The objective of the present work was to improve data acquisition and quantification of dynamic contrast‐enhanced perfusion imaging in the in vivo murine heart.
Four‐fold undersampled data were acquired in 14 mice and reconstructed using k‐t SPARSE. A two‐compartment exchange model was employed to provide additional characterization of myocardial tissue based on compartment volumes and the permeability...
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