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The hypothesis that regular treatment aimed at achieving and maintaining asthma control is accompanied by reduced airway hyper-responsiveness (AHR) was investigated.Adult patients (PC 20 methacholine <8 mg/ml, FEV 1 % predicted ≥70%) received salmeterol/fluticasone propionate combination 50/250 μg bd (SFC250) for a 12-week run-in; those achieving well-controlled (WC) asthma were...
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