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To analyse the role of thyroid hormones in development of the halibut Hippoglossus hippoglossus, a cDNA library was constructed from mRNA isolated from metamorphosing halibut larvae and approximately 500000 recombinants were screened using a probe derived from the thyroid hormone receptor (TR)-α gene of the frogXenopus laevis . A single positive clone was isolated and sequenced. It was found to contain...
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