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Background and Aims
The United States Food and Drug Administration has proposed regulation to require that cigarettes contain very low nicotine content (VLNC). In contrast, reducing the number of cigarettes per day (CPD) is the most common current method to reduce nicotine. This trial aims to explore whether gradually transitioning to VLNC cigarettes plus nicotine patch or reducing CPD plus nicotine...
Aims
To test whether, in comparison to usual care, brief motivational or reduction interventions increase quit attempts (QA) or abstinence among smokers who are not ready to quit.
Design
A parallel‐group randomized controlled trial of brief motivational (n = 185), reduction (n = 186) or usual care (n = 189) telephone interventions delivered over the course of 4 weeks. Outcomes were assessed at...
Aims Recent studies suggest that smoking cessation may cause more withdrawal symptoms than thought previously. The widely used Minnesota Withdrawal Scale (MWS‐R) was revised recently to include some of these newly described symptoms. We assessed the validity of MWS‐R and other proposed self‐reported measures of tobacco withdrawal symptoms.
Design and Setting An internet survey of daily and former...
Aims Clinical trials test the safety and efficacy of behavioral and pharmacological interventions in drug‐dependent individuals. However, there is no consensus about the most appropriate outcome(s) to consider in determining treatment efficacy or on the most appropriate methods for assessing selected outcome(s). We summarize the discussion and recommendations of treatment and research experts, convened...
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