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Human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) carries a distinct clinical behaviour. c-Met oncogene is an important driver for tumour progression and its relationship with HPV in OPSCC was explored in the present study.Knockdown of HPV oncogene E6 or p53 alone and in combination was performed to examine their effects on c-Met expression by Western blot and quantitative...
Both inducible nitric oxide synthase (iNOS) and peroxisome proliferator-activated receptor gamma (PPARγ) are closely associated with the development of human cancer. Although the expression of iNOS has been studied in non-small cell lung carcinoma (NSCLC), the level of PPARγ has not been examined in tumorous and non-tumorous tissues from NSCLC. The present study analysed the levels of both iNOS and...
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