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Schizophrenia is a chronic illness with a worldwide lifetime prevalence of about 1% [1]. Non-adherence and partial adherence to antipsychotic medication treatment is common and long-acting injectable “depot” preparations of antipsychotic medications have been used as an alternative to oral medication therapy for patients for whom adherence is a clinically significant problem [2].In present study,we...
Paliperidone extended-release (ER) is an atypical antipsychotic that presents the active metabolite of risperidone (9-hydroxyrisperidone) using OROS ® technology [1]. Multinational placebo-controlled studies have shown paliperidone ER 3- 15 mg/day to be both efficacious and safe, with discontinuation rates due to adverse events (AEs) similar to placebo [2].Seventy-eight female patients who...
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