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Coenzyme Q10 (CoQ10) is a provitamin synthesized via the 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase pathway, and thus may serve as a potential marker of intrinsic HMG-CoA reductase activity. HMG-CoA reductase inhibitors (statins) decrease CoQ10, although it is unclear whether this is due to reductions in lipoproteins, which transport CoQ10.We evaluated whether baseline plasma CoQ10...
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