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To develop and validate a lab-on-a-chip method to analyze exfoliated cells collected from a non-invasive brush biopsy in a NIDCR-sponsored 950-patient multi-site international clinical trial.Three groups of subjects (PMOD, OSCC, and normal controls) were enrolled at three American and one European sites in this prospective study. Matched brush and scalpel biopsies were collected from all non-control...