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Abstract. SU5416 is reported to be a selective inhibitor of vascular endothelial growth factor, and it has met with limited success in the clinic. In the present study, we investigated whether SU5416 could augment cisplatin-induced cytotoxicity in human ovarian cancer cells. When used as a single agent, 2-h exposures to SU5416 were not harmful to the cells up to doses of 100 M. For 48-h exposures,...
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