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Human glomerular microvascular endothelial cell (HGMEC) culture monolayers were maintained in static culture as controls or subjected to steady laminar shear stress of 0.5, 1.0, or 1.5 N/m 2 . Over 25 h of shear, the cumulative secretion of ET-1 was 705.4 pg/cm 2 in the control, 820.7 pg/cm 2 at 0.5 N/m 2 , 1063.2 pg/cm 2 at 1.0 N/m 2 , and 644.7 pg/cm...
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