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Background
Interleukin‐33 (IL‐33) is implicated as an epithelium‐derived danger signal promoting Th2‐dependent responses in asthma. We hypothesized that IL‐33 might also have direct effects on mast cell‐driven allergic airway obstruction.
Methods
The effects of IL‐33 on allergic responses in the airways of sensiti‐zed mice were assessed both in vivo and ex vivo, as well as on cultured mast cells...
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