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We hypothesized that ruxolitinib may inhibit the immune checkpoint protein, B7H3; and, thus, investigated its effects on this immune inhibitor using multiple myeloma (MM) cell lines, bone marrow (BM) mononuclear cells from MM patients and human MM LAGλ‐1A xenografts. Ruxolitinib reduced B7H3 gene and protein expression and increased IL‐2 and CD8 gene expression. These results suggest that ruxolitinib...
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