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In ageing cardiac β-adrenergic receptor (AR) function declines while little is known on muscarinic M 2 -R changes. To study possible mechanisms of β-AR and M 2 -R changes with age we assessed a) in vitro in right atria (RA) from 91 patients of different age (5 d-83 yrs) without apparent heart failure β-AR and M 2 -R densities. 10 μM GTP. 100 μM isoprenaline (ISO). 10 mM...
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