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The functional activity of P-glycoprotein (Pgp) was studied in Chinchilla rabbits after orchiectomy and administration of testosterone undecanoate after surgery. The functional activity of Pgp was determined by the pharmacokinetics of fexofenadine, its marker substrate. In addition, the localization of the transport protein was assessed in the liver, kidney, and jejunum by the immunohistochemistry...
Measurements of the coefficient of water molecules self-diffusion (D) and the time of spin-lattice relaxation (T1) in prosenchyme (elongated) plant cells, whose length significantly exceeding their transverse size, show that the orientation of plant tissues in the H0field significantly affects the measured parameters. We conclude that this effect should be taken into account in experiments on the...
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