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Virotherapy is emerging as an alternative treatment of cancer. Among the candidate oncolytic viruses (OVs), Newcastle disease virus (NDV) has emerged as a promising non-engineered OV. In the present communication, we explored the oncolytic potential of R2B Mukteshwar strain of NDV using SW-620 colon cancer cells. SW-620 cells were xenografted in nude mice and after evaluation of the safety profile,...
Summary.Results are presented for an experimental validation of the efficacy of an EU licensed, inactivated bovine viral diarrhoea virus vaccine (Bovilis BVDV). This study was designed to assess the quality of efficacy 6 months after a single course of vaccination (two intramuscular doses a month apart). A natural challenge at about 87 days of gestation by 3 persistently infected carrier heifers rapidly...
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