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Background Chronic T1 hypointense lesions in multiple sclerosis (MS) are areas of severe tissue destruction. The purpose of this study was to compare total water content (WC),myelin water content (MWC), magnetization transfer ratio (MTR), T1 relaxation time (T1), mean T2 relaxation time (GMT2) between stable MS lesions that are hypointense and isointense on T1-weighted images. Methods Six MS...
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