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Mammalian DNA polymerase β functions in the base excision DNA repair pathway filling in short patches (1–5 nt) in damaged DNA and removing deoxyribose 5′-phosphate from the 5′-side of damaged DNA. The backbone dynamics and the refined solution structure of the N-terminal domain of β-Pol have been characterized in order to establish the potential contribution(s) of backbone motion to the DNA binding...
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