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Benzodiazepines have been used for decades as first‐line treatment for status epilepticus (SE). For reasons that are not fully understood, the efficacy of benzodiazepines decreases with increasing duration of seizure activity. This often forces clinicians to resort to more drastic second‐ and third‐line treatments that are not always successful. The antiseizure properties of benzodiazepines are mediated...
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